I-TPN kwiMithi yanamhlanje: i-Evolution kunye ne-EVA Material Advancements

Ngaphezulu kweminyaka engama-25, isondlo esipheleleyo sabazali (TPN) siye sadlala indima ebalulekileyo kumayeza anamhlanje. Iqale yaphuhliswa nguDudrick neqela lakhe, olu nyango lugcina ubomi luphucule ngokumangalisayo amazinga okuphila kwizigulana ezinokusilela kwamathumbu, ngakumbi ezo zine-syndrome yamathumbu amafutshane. Ukulungiswa okuqhubekayo kwitekhnoloji ye-catheter kunye neenkqubo zokuxilisa, ezidityaniswe nengqiqo enzulu kwiimfuno ze-metabolic, zivumele ukuqulunqwa kwesondlo esilungelelanisiweyo esilungiselelwe iimfuno zesigulana ngasinye. Namhlanje, i-TPN imele njengento ebalulekileyo yonyango, kunye nezicelo ezicacileyo zeklinikhi kunye neprofayili yokhuseleko ebhalwe kakuhle. Phakathi kwabo,Iingxowa ze-TPNezenziwe ngezinto ze-EVA ziye zaba sisisombululo esikhethiweyo sokupakishwa kwenkxaso yesondlo seklinikhi kunye nekhaya ngenxa ye-biocompatibility yabo egqwesileyo, ukuzinza kweekhemikhali kunye nokhuseleko lwexesha elide lokugcina. Ukutshintshela kulawulo olusekelwe ekhaya kuye kwaphucula ngakumbi ukusebenza kwawo, ukunciphisa iindleko zokulaliswa esibhedlele ngelixa kugcinwa ukusebenza kakuhle. Abaphandi ngoku baphanda izinto ezinokuthi zisetyenziswe kwi-TPN, kubandakanywa nendima yayo ekulawuleni iimeko ezingapheliyo ezifana ne-atherosclerosis.

Ngaphambi kokuqalisa i-TPN, uvavanyo olucokisekileyo lwezondlo luyimfuneko ukuze kulungiswe iziphumo zonyango. Amacandelo abalulekileyo okuvavanya abandakanya ukuphonononga imbali yonyango yesigulane ngokulahleka kwesisindo esibalulekileyo (i-10% okanye ngaphezulu), ubuthathaka bemisipha kunye ne-edema. Uvavanyo lomzimba kufuneka lugxininise kwimilinganiselo ye-anthropometric, ngakumbi i-triceps skinfold thick, enika ukuqonda okubalulekileyo kwi-fat reserves. Uvavanyo lwaselabhoratri lubandakanya amanqanaba e-albumin kunye ne-transferrin, iimpawu ezisetyenziswa ngokubanzi zesimo seprotheyini, nangona iimvavanyo ezikhethekileyo ezifana neprotein ebopha i-retinol zinokunika ulwazi olongezelelweyo xa lukhona. Umsebenzi we-immune unokuvavanywa ngokubala kwe-lymphocyte iyonke kunye nokulibaziseka kovavanyo lwesikhumba se-hypersensitivity kunye ne-antigens eziqhelekileyo ezifana ne-PPD okanye i-Candida.

Isixhobo esiluncedo kakhulu sokuqikelela i-Prognostic Nutritional Index (PNI), edibanisa iiparamitha ezininzi kwinqaku elinye lomngcipheko:

I-PNI (%) = 158 - 16.6 (serum albumin in g / dL) - 0.78 (triceps skinfold in mm) - 0.20 (transferrin in mg / dL) - 5.8 (hypersensitivity score).

Izigulane ezine-PNI engaphantsi kwe-40% zinomngcipheko ophantsi weengxaki, ngelixa abo bafumana i-50% okanye ngaphezulu bejongene nomngcipheko wokufa ophakamileyo omalunga nama-33%. Le ndlela yokuhlola ebanzi inceda oogqirha ukuba benze izigqibo ezinolwazi malunga nexesha lokuqalisa i-TPN kunye nendlela yokubeka iliso ekusebenzeni kwayo, ekugqibeleni kuphuculwe ukunakekelwa kwesigulane kwimimiselo enzima kunye nengapheliyo. Ukudityaniswa kwenkxaso yesondlo ephucukileyo kunye neeprothokholi zovavanyo olungqongqo kuhlala kusisiseko sonyango lwangoku.

Njengenkxaso ebalulekileyo yonyango lwe-TPN, inkampani yethu ibonelela ngeengxowa eziphezulu ze-EVA eziphathekayo ze-TPN. Iimveliso zilandela ngokungqongqo imigangatho yamazwe ngamazwe, ziye zadlula i-FDA kunye nesatifikethi se-CE, kwaye ziye zamkelwa ngokubanzi kwiimarike ezininzi kwihlabathi jikelele, zibonelela ngezisombululo ezikhuselekileyo nezithembekileyo zonyango lwezonyango kunye nesondlo sasekhaya.