Ngawaphi amachiza athintela ukukhanya?

Iziyobisi ezikhanyayo zibhekisela kumachiza afunekayo ukuba agcinwe kwaye asetyenziswe ebumnyameni, kuba ukukhanya kuya kukhawulezisa i-oxidation yeziyobisi kwaye kubangele ukuchithwa kwe-photochemical, okunganciphisi nje amandla eziyobisi, kodwa kuvelisa utshintsho lombala kunye nemvula, echaphazela kakhulu umgangatho wamachiza, kwaye kwanokwandisa i-toxicity yeziyobisi. Amachiza angangenwa ukukhanya ahlulahlulwe abe ngamachiza akwibakala elikhethekileyo angangenwa lula, akwibakala lokuqala angangenwa lula, akwinqanaba lesibini angangenwa ukukhanya, kunye nawokudidi lwesithathu amayeza angangenwa ukukhanya.

1. Iziyobisi ezikhethekileyo zokukhanya ukukhanya: ikakhulukazi i-nitroprusside ye-sodium, i-nifedipine kunye nezinye iziyobisi, ngakumbi i-nitroprusside ye-sodium, enozinzo olubi. Kukwayimfuneko ukusebenzisa iisirinji ezinobungqina bokukhanya, iityhubhu zokufakela, okanye iifoyile ze-aluminium opaque ngexesha lolawulo lokufakwa. Ukuba izinto ezisetyenziselwa ukugubungela i-syringe, ukuba ukukhanya kuchithwa kumnyama omnyama, i-orange okanye izinto eziluhlaza okwesibhakabhaka, kufuneka kukhutshazwe ngeli xesha;

2. Amachiza odidi lokuqala athintela ukukhanya: ikakhulu aquka amayeza okubulala iintsholongwane e-fluoroquinolone afana ne-levofloxacin hydrochloride kunye ne-gatifloxacin, kunye neziyobisi ezifana ne-amphotericin B kunye ne-doxorubicin. I-antibiotics ye-Fluoroquinolone kufuneka ithintele ukukhanya kwelanga ngokugqithiseleyo kunye nemitha ye-ultraviolet eyenziweyo ukuthintela ukuvela kwe-photosensitivity reaction kunye ne-toxicity. Umzekelo, i-levofloxacin hydrochloride inokubangela ukusabela okunqabileyo kwe-phototoxic (iziganeko<0.1%). Ukuba iimpendulo ze-phototoxic zenzeka, ichiza kufuneka lipheliswe;

3. Iziyobisi yesibini ukuphepha ukukhanya: kubandakanywa nimodipine kunye namanye amachiza antihypertensive, promethazine kunye nezinye antihistamines, chlorpromazine kunye namanye amachiza antipsychotic, cisplatin, cyclophosphamide, methotrexate, cytarabine Amachiza Anti-ithumba, kwakunye iivithamini amanzi-enyibilikayo, epinephrine, nezinye iziyobisi kwi-dopamine, i-morphine kufuneka zigcinwe ngokukhawuleza kwaye zigcinwe kwi-dispen morphine. i-oxidation kunye ne-hydrolysis;

4. Amachiza akwinqanaba eliphezulu akhusela ukukhanya: njengeevithamini ezinyibilikayo kumafutha, imethylcobalamin, ihydrocortisone, iprednisone, ifurosemide, ireserpine, iprocaine hydrochloride, i-pantoprazole sodium, i-etoposide, Amayeza afana nedocetaxel, i-ondansetron, ne-nitroglycerin onke abuthathaka ekukhanyeni kwaye agcinwe ebumnyameni.